ADJUNCT PROFESSOR EMERITUS
Jeanne directs the Research on Autism and Development Laboratory. She is a Clinical Neuropsychologist and Cognitive Neuroscientist whose focus is on the identification of brain structural and functional correlates of cognitive function, particularly dynamic attentional processes, and developmental changes in these relationships.
STAFF RESEARCH ASSOCIATE
Sarah is currently the staff research associate at RADLab, assisting in recruiting for and developing new studies that help us understand the cognitive performance of individuals with ASD.
Trent L. Simmons
Most psychiatric interventions are implemented in the absence of knowledge about individual variation in important domains of brain function that might influence therapeutic response and outcome. This “one-size-fits-all” approach to treatment is problematic, with treatment failure occurring far too often and incurring substantial cost to the patient, family, therapist and larger social system. To “bend the curve” on the individual outcomes and societal impact of chronic psychotic illness, we must advance our understanding of the neural substrates of the illness features that most strongly contribute to poor outcomes, and use this information to guide mechanistically informed, personalized treatments. My program of research has advanced the use of neurophysiological biomarkers to develop precision medicine trials for psychosis patients that are: 1) effectively delivered in “real-world” community centers; and 2) informed by objective, reliable, validated, and low-cost biomarkers for identifying patients most likely to benefit (or not) from treatments. Findings support large-scale biomarker-guided trials to prevent or ameliorate illness in high-risk cohorts or treatment refractory populations. This program ultimately aims to develop and apply personalized biomarker assessment tools to deliver the “right treatment” to the “right person” at the “right time.
ASSOCIATE PROJECT SCIENTIST